Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension is a rare but life-threatening disease, characterised by high blood pressure in pulmonary arteries.  Pulmonary arteries are blood vessels that carry blood from the heart to the lungs, for oxygen saturation.

As pulmonary arterial pressures increase, it becomes more and more difficult for the heart to pump blood through the lungs. Progressively, the heart struggles to pump against these high pressures, and this may ultimately lead to heart failure.

Pulmonary Arterial Hypertension can occur with no known underlying cause, or it can occur in association with other conditions such as connective tissue disease, congenital heart defects, portal hypertension or administration of other medicines such as anorexigens.

Pulmonary Arterial Hypertension is a rare disease that can affect people at any age. Its incidence is estimated to be 15-50 cases / million population. Worldwide, approximately 200,000 people are affected by Pulmonary Arterial Hypertension, while it is almost twice as common in women as men. The disease is more common in certain high risk groups, such as scleroderma patients and patients of congenital heart defects. In Greece, it is estimated that there are 350-550 Pulmonary Arterial Hypertension patients.

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